| 发明名称 |
ATTENUATED MUTANTS OF SALMONELLA WHICH CONSTITUTIVELY EXPRESS THE VI ANTIGEN |
| 摘要 |
Attenuated Salmonella mutants which constitutively express the Vi antigen are disclosed, as well as vaccines against typhoid fever containing the same, live vector vaccines containing the same, and DNA-mediated vaccines containing the same.
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| 申请公布号 |
CA2328056(C) |
申请公布日期 |
2010.07.06 |
| 申请号 |
CA19992328056 |
申请日期 |
1999.04.30 |
| 申请人 |
UNIVERSITY OF MARYLAND, BALTIMORE |
发明人 |
NORIEGA, FERNANDO R.;SZTEIN, MARCELO;LEVINE, MYRON M. |
| 分类号 |
C12N1/21;C12N15/09;A61K39/00;A61K39/02;A61K39/08;A61K39/112;A61K48/00;A61P31/04;A61P37/04;C07K14/255;C12N1/20;C12N1/36;C12N15/74;C12R1/42 |
主分类号 |
C12N1/21 |
| 代理机构 |
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代理人 |
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| 主权项 |
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