发明名称 |
RADIOACTIVE CELL LABELING AGENT |
摘要 |
PURPOSE: A composition containing radioactive marker compound is provided to label cells in a high efficiency and to detect movement of labeled cell movement. CONSTITUTION: A radioactive marker compound is represented by chemical formula 1. In chemical formula 1, X is iodine radioactive isotope. A composition contains radioactive marker compound of chemical formula 1 or 2. A method for manufacturing the radioactive marker compound comprises: a step of reacting oleyl alcohol, 4-iodobenzoyl chloride, methylene chloride, and triethylamine to obtain oleyl-4-iodobenzoate of chemical formula 5; a step of reacting the oleyl-4-iodobezoate with hexabutylditin and tetrakis(triphenylphosphine)palladium to obtain a compound of chemical formula 6; and a step of reacting the compound of chemical formula 6 with radioactive iodine metal salt.
|
申请公布号 |
KR20100075412(A) |
申请公布日期 |
2010.07.02 |
申请号 |
KR20090130673 |
申请日期 |
2009.12.24 |
申请人 |
KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION |
发明人 |
YOO, JEONG SOO;JEON, HAK RIM;DARPAN NAVINCHANDRA PANDYA;LEE, HWA YOUNG;OH, JI EUN |
分类号 |
C07F13/00;G01N33/60 |
主分类号 |
C07F13/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|