The present invention is directed toward a method of treating a subject for a condition mediated by aberrant Wnt/ß-catenin signaling by selecting a subject with a condition mediated by aberrant Wnt/ß-catenin signaling and administering to the selected subject a compound selected from the group consisting of those set forth in Table 1, Table 2, and a pharmaceutically acceptable salt thereof. A method of similarly modulating the Wnt/ ß-catenin pathway in a subject is also discussed.
申请公布号
WO2010075286(A1)
申请公布日期
2010.07.01
申请号
WO2009US69003
申请日期
2009.12.21
申请人
UNIVERSITY OF WASHINGTON;MASSACHUSETTS INSTITUTE OF TECHNOLOGY;MOON, RANDALL, T.;BIECHELE, TRAVIS, L.;CAMP, NATHAN, D.;HAGGARTY, STEPHEN;FASS, DANIEL
发明人
MOON, RANDALL, T.;BIECHELE, TRAVIS, L.;CAMP, NATHAN, D.;HAGGARTY, STEPHEN;FASS, DANIEL