发明名称 PYRROLIDINE DERIVATIVES AS NK-3 RECEPTOR ANTAGONISTS
摘要 The present invention relates to a compound of formula I wherein Ar1, Ar2, R1, R2, R3, n, o, and p are as described herein or to a pharmaceutically active salt, to all stereoisomeric forms, including individual diastereoisomers and enantiomers as well as to racemic and non-racemic mixtures thereof. Compounds of the invention are high potential NK-3 receptor antagonists for the treatment of depression, pain, psychosis, Parkinson's disease, schizophrenia, anxiety and attention deficit hyperactivity disorder (ADHD).
申请公布号 US2010168088(A1) 申请公布日期 2010.07.01
申请号 US20090572282 申请日期 2009.10.02
申请人 BISSANTZ CATERINA;JABLONSKI PHILIPPE;KNUST HENNER;NETTEKOVEN MATTHIAS;PATINY-ADAM ANGELIQUE;RATNI HASANE;RIEMER CLAUS 发明人 BISSANTZ CATERINA;JABLONSKI PHILIPPE;KNUST HENNER;NETTEKOVEN MATTHIAS;PATINY-ADAM ANGELIQUE;RATNI HASANE;RIEMER CLAUS
分类号 A61K31/541;A61K31/40;A61K31/4025;A61K31/4155;A61K31/4178;A61K31/4184;A61K31/4192;A61K31/4196;A61K31/422;A61K31/4245;A61K31/427;A61K31/437;A61K31/4375;A61K31/4439;A61K31/496;A61K31/497;A61K31/506;A61K31/5377;A61P25/04;A61P25/16;A61P25/18;A61P25/22;A61P25/24;C07D207/14;C07D401/06;C07D401/14;C07D403/06;C07D403/10;C07D405/10;C07D413/10;C07D413/14;C07D417/10;C07D471/04 主分类号 A61K31/541
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