Disclosed herein are oral dosage forms and methods of their use, in particular oral dosage systems for the delivery of estriol compounds. Embodiments described herein relate to rapidly disintegrating oral dosage formulations that disintegrate in the saliva of the buccal and/or sublingual and/or esophageal cavity. Oral dosage forms described herein relate to stabilized amorphous and nanocrystalline forms of the active ingredients of the formulations.
申请公布号
WO2010033832(A3)
申请公布日期
2010.07.01
申请号
WO2009US57524
申请日期
2009.09.18
申请人
EVESTRA, INC.;SHAKED, ZE'EV;ELGER, WALTER;NICKISCH, KLAUS