COMPOUNDS AND METHODS FOR THE TREATMENT OF AUTOIMMUNE AND INFLAMMATORY DISEASE
摘要
<p>The present invention provides a method and composition for the treatment and prevention of an autoimmune disease such a multiple sclerosis which is mediated by autoreactive T cells. The administration of a NOD-1 agonist is shown to mediate an anti-inflammatory immune response. NOD-1 agonists suitable for use in the methods and compositions of the invention include diaminopimelic acid (DAP)-containing muropeptide compounds such as Tri-DAP and M-TriDAP.</p>
申请公布号
WO2010072797(A1)
申请公布日期
2010.07.01
申请号
WO2009EP67819
申请日期
2009.12.22
申请人
THE PROVOST, FELLOWS AND SCHOLARS OF THE HOLY ANDUNDIVIDED TRINITY OF QUEEN ELIZABETH, NEAR DUBLIN;MILLS, KINGSTON;HIGGINS, SARAH