发明名称 |
METHOD FOR PRODUCTION OF ANTIBODY |
摘要 |
Disclosed is a method for producing a recombinant antibody efficiently and at a low cost. Specifically disclosed is a method for producing an antibody or a fragment thereof, which comprises producing the antibody or the fragment thereof by using a cell which contains a higher copy number of foreign DNA encoding an L-chain of the antibody or a fragment thereof compared with the copy number of foreign DNA encoding an H-chain of the antibody or a fragment thereof. Also disclosed are: a recombinant vector carrying one copy of DNA encoding an H-chain of an antibody or a fragment thereof and two or more copies of DNA encoding an L-chain of the antibody or a fragment thereof; a transformed cell; and others. |
申请公布号 |
KR20100074184(A) |
申请公布日期 |
2010.07.01 |
申请号 |
KR20107008087 |
申请日期 |
2008.10.14 |
申请人 |
CHUGAI SEIYAKU KABUSHIKIKAISHA |
发明人 |
YAMADA YOSHIKI;KIYASU TATSUYA;TABATA KAZUYUKI;KUZUMAKI AKIHIRO;YAMASHIRO MAI |
分类号 |
C12N15/13;C07K16/18;C12N15/85 |
主分类号 |
C12N15/13 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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