发明名称 |
Methods and Compositions for Prevention or Treatment of RSV Infection Using Modified Duplex RNA Molecules |
摘要 |
Methods and compositions are provided for the prevention or treatment of RSV infection in a human. The methods include administering one or more doses of a composition comprising an siRNA. The dose can be formulated for topical or parenteral administration. Topical administration includes administration as a nasal spray, or by inhalation of respirable particles or droplets. The siRNA preferably comprises a sense strand and antisense strand with modified nucleotides.
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申请公布号 |
US2010168205(A1) |
申请公布日期 |
2010.07.01 |
申请号 |
US20090605299 |
申请日期 |
2009.10.23 |
申请人 |
ALNYLAM PHARMACEUTICALS, INC. |
发明人 |
MEYERS RACHEL;ALVAREZ RENE;COLE GEOFF;ELBASHIR SAYDA |
分类号 |
A61K31/713;A61P31/14;C07H21/02 |
主分类号 |
A61K31/713 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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