发明名称 Octanoate-Reduced Human Albumin
摘要 The invention relates to the improvement of the transport properties of albumin which is produced on an industrial scale, e.g. via the Cohn process or by means of recombinant processes, and is mixed, during the production process, with substances that saturate the binding points on the albumin and thus affect the binding properties and transport properties of the final product. A special embodiment of the invention relates to pasteurized and then octanoate-reduced human albumin for therapeutic use, especially in a detoxification treatment of human plasma, e.g. for the intravenous treatment of acute or chronic liver diseases, and as a dialysate in extracorporeal liver dialysis with albumin in the molecular adsorbent recirculating system (MARS) or in single-pass dialysis.
申请公布号 US2010168000(A1) 申请公布日期 2010.07.01
申请号 US20060086867 申请日期 2006.12.13
申请人 KIESSLING PETER;BOSSE DIETRICH;ZEISS JOHANNES;DIDERRICH GASTON 发明人 KIESSLING PETER;BOSSE DIETRICH;ZEISS JOHANNES;DIDERRICH GASTON
分类号 A61K38/38;A61P39/04;C07K14/76 主分类号 A61K38/38
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