发明名称 |
Compositions and Methods for Determining Whether a Subject Would Benefit from Co-Receptor Inhibitor Therapy |
摘要 |
The present invention provides methods and compositions for determining whether a subject would benefit from co-receptor inhibitor therapy. In certain aspects, the methods can be used to determine whether a subject infected with a dual-mixed tropic population of HIV would benefit from CCCR5-inhibitor therapy or CXCR4-inhibitor therapy, the methods comprising determining whether the HIV population is a homogeneous or heterogeneous population of HIV, wherein the nature of the homogenous or heterogenous population of HIV indicates whether the patient would benefit from co-receptor inhibitor therapy.
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申请公布号 |
US2010167266(A1) |
申请公布日期 |
2010.07.01 |
申请号 |
US20080527863 |
申请日期 |
2008.02.26 |
申请人 |
HUANG WEI;FRANSON SIGNE;PETROPOULOS CHRISTOS J;TOMA JONATHAN;WHITCOMB JEANNETTE |
发明人 |
HUANG WEI;FRANSON SIGNE;PETROPOULOS CHRISTOS J.;TOMA JONATHAN;WHITCOMB JEANNETTE |
分类号 |
C12Q1/70 |
主分类号 |
C12Q1/70 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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