ANTISENSE OLIGONUCLEOTIDES FOR MODIFYING EXPRESSION OF ACC1 AND ACC2 AND FOR CONTROLLING METABOLIC DISORDERS
摘要
Disclosed herein are compounds, compositions and methods for modulating the expression of ACCl or ACC2 or both in a cell, tissue or animal. Also provided are uses of disclosed compounds and compositions in the manufacture of a medicament for treatment of diseases and disorders.
申请公布号
WO2006110775(A3)
申请公布日期
2010.07.01
申请号
WO2006US13536
申请日期
2006.04.10
申请人
ISIS PHARMACEUTICALS, INC.;BHANOT, SANJAY;MONIA, BRETT, P.;GEISLER, JOHN;MCKAY, ROBERT;DOBIE, KENNETH, W.
发明人
BHANOT, SANJAY;MONIA, BRETT, P.;GEISLER, JOHN;MCKAY, ROBERT;DOBIE, KENNETH, W.