发明名称 |
Genipin Derivatives and Uses Thereof |
摘要 |
Genipin derivatives and pharmaceutical compositions thereof that inhibit the activity of uncoupling protein-2 (UCP2) and are useful in treating deficient first-phase insulin secretion, non-insulin dependent diabetes mellitus, and ischemia in a mammal are disclosed.
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申请公布号 |
US2010168160(A1) |
申请公布日期 |
2010.07.01 |
申请号 |
US20090622296 |
申请日期 |
2009.11.19 |
申请人 |
BETH ISRAEL DEACONESS MEDICAL CENTER , INC. AND TRUSTEES OF BOSTON UNIVERSITY |
发明人 |
ZHANG CHEN-YU;LOWELL BRADFORD B.;PORCO, JR. JOHN A.;SHEN RUICHAO;LIN CHENG T.;KRAUSS STEFAN |
分类号 |
A61K31/4725;A61K31/352;A61K31/365;A61K31/472;C07D211/90;C07D217/22;C07D221/04;C07D309/32;C07D311/94;C07D401/02;C07D491/04;C07D493/04;C07D493/06;C07D493/18 |
主分类号 |
A61K31/4725 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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