Co-culture compositions and methods are described for identifying agents that modulate a cellular phenotype, particularly of neurons or pancreatic beta cells are provided herein, where the methods include co-culturing differentiated cells, wherein at least one of the cell-types are derived from human induced pluripotent stem cells from a subject having or predisposed to a neurodegenerative or metabolic disorder. Co-culture compositions of differentiated cells from two different human subjects are also described.
申请公布号
WO2010042669(A3)
申请公布日期
2010.07.01
申请号
WO2009US59910
申请日期
2009.10.07
申请人
IPIERIAN, INC.;ELIAS, GUILLERMO, MUNOZ;JAVAHERIAN, ASHKAN;IRION, STEFAN
发明人
ELIAS, GUILLERMO, MUNOZ;JAVAHERIAN, ASHKAN;IRION, STEFAN