发明名称 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE COMPOUNDS USING TRANSFER HYDROGENATION
摘要 <p>A catalytic process for the preparation of optically active compounds and their conversion thereafter to desired drag substances. In particular, the process relates to the preparation of (S)-3-(1-Dimethylamino-ethyl)-phenol using asymmetric catalytic reduction and transfer hydrogenation, thereby providing an improved route to forming drug substances such as rivastigimine and rivastigimine hydrogen tartrate.</p>
申请公布号 WO2010072798(A1) 申请公布日期 2010.07.01
申请号 WO2009EP67821 申请日期 2009.12.23
申请人 NOVARTIS AG;MATHES, CHRISTIAN;FOULKES, MICHAEL;KESSELGRUBER, MARTIN 发明人 MATHES, CHRISTIAN;FOULKES, MICHAEL;KESSELGRUBER, MARTIN
分类号 C07B53/00;C07C37/00;C07C39/11;C07C213/08;C07C215/50;C07C269/06;C07C271/44;C07C309/64 主分类号 C07B53/00
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