发明名称 |
APPLICATION OF 99MTC PEPTIDE-BASED COMPOUND AS A BONE MARROW IMAGING AGENT |
摘要 |
<p>The present invention relates to methods and materials involved in using peptide-based compounds in bone marrow imaging. More specifically the invention relates to the use of 99mTc peptide-based compounds as targeting vectors that bind to receptors associated with angiogenesis, in particular integrin receptors, e.g. the avß3 integrin receptor. Such contrast agents may thus be used for diagnosis of haemolytic anaemia, myeloproliferative disorders, myelofibrosis, selection of biopsy sites, and early detection of skeletal metastatasis as well as detecting avascular necrosis of the femoral heads.</p> |
申请公布号 |
WO2010075058(A1) |
申请公布日期 |
2010.07.01 |
申请号 |
WO2009US67987 |
申请日期 |
2009.12.15 |
申请人 |
GE HEALTHCARE LIMITED;MEDI-PHYSICS, INC.;EVANS, PAUL;MCPARLAND, BRIAN;ZUBELDIA, JOSE |
发明人 |
EVANS, PAUL;MCPARLAND, BRIAN;ZUBELDIA, JOSE |
分类号 |
G01N33/574;G01N33/68 |
主分类号 |
G01N33/574 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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