发明名称 |
INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 7 FOR TREATMENT OF CANCER |
摘要 |
<p>Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an effective amount of an IGFBP7 agent if the tumor has increased Ras-BRAF-MEK-Erk signaling, is dependent for growth and/or survival upon the Ras-BRAF-MEK-Erk signaling pathway, and/or expresses an activated or oncogenic BRAF or RAS.</p> |
申请公布号 |
EP2201562(A2) |
申请公布日期 |
2010.06.30 |
申请号 |
EP20080830697 |
申请日期 |
2008.09.11 |
申请人 |
UNIVERSITY OF MASSACHUSETTS |
发明人 |
GREEN, MICHAEL;WAJAPEYEE, NARENDRA |
分类号 |
G10K15/02;A61K38/17;A61P35/00 |
主分类号 |
G10K15/02 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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