发明名称 |
DETECTION OF SALIVA PROTEINS MODULATED SECONDARY TO DUCTAL CARCINOMA IN SITU OF THE BREAST |
摘要 |
<p>A method of differentiating among the presence of ductal carcinoma in situ in the breast, benign fibroadenoma of the breast, and non-cancerous breast tissue in a subject is disclosed. The method comprises: measuring the concentration of at least one protein biomarker selected from a group of forty-nine differentially expressed proteins in the saliva of persons with DCIS, or benign fibroadenoma, or in persons who are cancer-free. The resulting test data is compared to a reference panel. From the comparison the presence in the subject of either ductal carcinoma in situ of the breast, or benign fibroadenoma of the breast is determined.</p> |
申请公布号 |
EP2201363(A2) |
申请公布日期 |
2010.06.30 |
申请号 |
EP20080832313 |
申请日期 |
2008.09.11 |
申请人 |
THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM |
发明人 |
STRECKFUS, CHARLES, F.;DUBINSKY, WILLIAM, P.;BIGLER, LENORA, R. |
分类号 |
G01N33/48;C12Q1/68;G01N33/53 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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