发明名称 |
PROCESS FOR PRODUCING A CAPSULAR POLYSACCHARIDE FOR USE IN CONJUGATE VACCINES |
摘要 |
A method for producing a polysaccharide and a conjugate vaccine including the polysaccharide produced according to the method. A characteristic step in the method is that the pH of the culture medium is kept at a constant value with base or acid until adjustment with respectively base or acid is not possible anymore. Using the method, capsular polysaccharide may be obtained in a high yield in a relatively short time. The method is straightforward, reproducible and cost-effective. |
申请公布号 |
SI1664319(T1) |
申请公布日期 |
2010.06.30 |
申请号 |
SI20040031412T |
申请日期 |
2004.09.10 |
申请人 |
AN VWS DE STAAT DER NEDERLANDEN, VERT. DOOR DE MINISTER V |
发明人 |
HAMIDI AHD;BEURRET MICHEL FRANCOIS |
分类号 |
A61K39/102;A61K39/385;A61K47/48;C12P19/04 |
主分类号 |
A61K39/102 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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