发明名称 IDENTIFICATION OF HLA-A2 PRESENTED T-CELL EPITOPES DERIVED FROM THE ONCOFETAL ANTIGEN-IMMATURE LAMININ RECEPTOR PROTEIN AND USES THEREOF
摘要 The present invention relates to immunotherapeutic methods, and molecules and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer, in particular several tumor entities including hematological malignancies. The present invention furthermore relates to tumor-associated T-helper cell peptide epitopes, alone or in combination with other tumor-associated peptides, that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumor immune responses. In particular, the present invention relates to two novel peptide sequences derived from HLA class I or Il molecules of human oncofoetal antigen immature laminin receptor (OFA/iLR) which can be used in vaccine compositions for eliciting anti-tumor immune responses.
申请公布号 EA013598(B1) 申请公布日期 2010.06.30
申请号 EA20070002202 申请日期 2006.04.26
申请人 IMMATICS BIOTECHNOLOGIES GMBH 发明人 ZEIS MATTHIAS
分类号 C07K14/47;A61K39/00;A61P35/00;C07H21/00;C07K14/705;C12N15/00 主分类号 C07K14/47
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