| 发明名称 |
HETEROBICYCLIC METALLOPROTEASE INHIBITORS AND USE THEREOF |
| 摘要 |
The present invention relates generally to amide group containing pharmaceutical agents, and in particular, to amide containing heterobicyclic metalloprotease inhibitor compounds. More particularly, the present invention provides a new class of heterobicyclic MMP- 13 inhibiting compounds, that exhibit an increased potency in relation to currently known MMP- 13 inhibitors. |
| 申请公布号 |
EA013525(B1) |
申请公布日期 |
2010.06.30 |
| 申请号 |
EA20070002568 |
申请日期 |
2006.05.22 |
| 申请人 |
ALANTOS-PHARMACEUTICALS, INC. |
发明人 |
STEENECK CHRISTOPH;GEGE CHRISTIAN;RICHTER FRANK;HOCHGUERTEL MATTHIAS;FEURSTEIN TIM;BLUHM HARALD;SUCHOLEIKI IRVING;BOER JURGEN;WU XINYUAN;SCHNEIDER MATTHIAS;NOLTE BERT;GALLAGHER BRIAN;VAN VELDHUIZEN JOSHUA;DENG HONGBO;ESSERS MICHAEL;KROTH HEIKO;KIELY ANDREW;POWERS TIMOTHY;TAVERAS ARTHUR, G. |
| 分类号 |
C07D487/04;A61K31/519;A61P19/00 |
主分类号 |
C07D487/04 |
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