发明名称 |
COMPOSITIONS FOR THE TRANSFECTION OF CELLS |
摘要 |
<p>The present invention relates to the targeted delivery of molecules to cells expressing toll-like receptors (TLRs). Aspects of the invention provide compounds comprising a positively charged group linked to a TLR ligand. These compounds are useful for in vitro and in vivo methods of transfection of TLR-expressing cells. Other aspects of the invention relate to the use of such compounds for repression of gene expression and DNA vaccination approaches.</p> |
申请公布号 |
EP2200638(A1) |
申请公布日期 |
2010.06.30 |
申请号 |
EP20080800135 |
申请日期 |
2008.10.09 |
申请人 |
THE UNIVERSITY OF MELBOURNE |
发明人 |
JACKSON, DAVID CHARLES;ZENG, WEIGUANG;CHUA, BRENDON YEW LOONG |
分类号 |
A61K39/00;C07K1/107;C12N15/87 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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