发明名称 Substituted Benzoylamino-indan-2-carboxylic acids and related compounds
摘要 The present invention relates to novel compounds of the formula Ia: in any of its stereoisomeric forms or a mixture of stereoisomeric forms in any ratio, or a physiologically acceptable salt thereof, wherein the substituents are as described herein. The inventive compounds have CXCR5 inhibitory activity, and are particularly useful in treating or preventing various inflammatory diseases, such as rheumatoid arthritis, multiple sclerosis, lupus, Crohn's Disease, associated with the modulation of the human CXCR5 receptor.
申请公布号 ZA200907414(B) 申请公布日期 2010.06.30
申请号 ZA20090007414 申请日期 2009.10.22
申请人 SANOFI-AVENTIS 发明人 CAULFIELD, THOMAS, J;CLEMENS, JENNIFER;FRANCIS, ROBERT S.;FREED, BRIAN, S;JOHN, STANLY;LE, TIEU-BINH;PEDGRIFT, BRIAN;RAMOS, ANTONIO, D.;ROSSE, GERARD;SMRCINA, MARTIN;THORPE, DAVID, S.;WIRE, WILLIAM;ZHAO, JIANHONG
分类号 A61K;A61P;C07C;C07D 主分类号 A61K
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