| 摘要 |
A method of treating or preventing a condition related to an HPV infection is provided. The method comprises administering to a subject a composition comprising a purified Hsp65-E7 fusion protein (HspE7) admixed with an immune stimulant selected from the group consisting of CpG, a TLR3 agonist such as PolyI:C, PolyICLC, mono-phosphoryl-lipid A (MPL), MPL-trehalose 6,6′-dimycolate (MPL-TDM), and anti-CD40. A composition comprising HspE7 and one or more than one of CpG, a TLR3 agonist such as PolyI:C, PolyICLC, MPL, MPL-TDM, and anti-CD40, and method of reducing a tumor or virus development in a mammal or subject in need thereof by using the composition are also provided. |
