发明名称 Process for production of prasugrel hydrochloride having high purity
摘要 An object of the present invention is to provide prasugrel hydrochloride with a reduced content of CATP, and the like. In the formulae, R represents a protecting group for a hydroxyl group. A method for producing prasugrel hydrochloride represented by the above formula is provided, characterized by comprising, in step (i), controlling, at low values, the temperature during the addition, optionally dropwise, of a chlorinating agent and the reaction temperature after the addition, optionally dropwise, of the chlorinating agent.
申请公布号 ZA200906850(B) 申请公布日期 2010.06.30
申请号 ZA20090006850 申请日期 2009.10.01
申请人 DAIICHI SANKYO COMPANY, LIMITED;UBE INDUSTRIES, LTD. 发明人 MIYATA, HIROYUKI;WADA, YUKINORI;YOKOTA, NAOYUKI
分类号 A61K;A61P;C07D 主分类号 A61K
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