发明名称 |
Multi-valent guanidinium compounds for enhancing molecular translocation across cellular membranes and epithelial tissues |
摘要 |
Disclosed herein are guanidinium containing compounds consisting of a core moiety with a plurality of side chains containing guanidinium groups. Such compounds have enhanced translocation across cellular membranes and epithelial tissues. The compounds may also have a therapeutic or other biologically active moiety attached so that these moieties may be effectively transported into a cell by the guanidinium containing compound.
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申请公布号 |
US7745392(B2) |
申请公布日期 |
2010.06.29 |
申请号 |
US20060525512 |
申请日期 |
2006.09.21 |
申请人 |
NITTO DENKO CORPORATION |
发明人 |
HOU ZHENG;LIU JIAN;YU LEI |
分类号 |
A61K31/155;A61K31/395;A61K38/08;A61K38/12;C07C279/00;C07K7/06;C07K7/64 |
主分类号 |
A61K31/155 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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