发明名称 |
Devices and methods for analyte detection using distorted liquid crystals |
摘要 |
The present invention provides devices and methods for detection of analytes based on measuring the anchoring strength of liquid crystals having distorted geometries. Methods for detecting an analyte in a sample include the steps of: (a) capturing an analyte on a substrate surface wherein the substrate surface defines an easy axis when in contact with a liquid crystal. Substrate surface and liquid crystal are brought into contact and an analyte-dependent departure in the orientation of the liquid crystal from the easy axis of the substrate surface is measured. This departure indicates the presence of the analyte in the sample. |
申请公布号 |
US7745220(B2) |
申请公布日期 |
2010.06.29 |
申请号 |
US20060542432 |
申请日期 |
2006.10.03 |
申请人 |
WISCONSIN ALUMNI RESEARCH FOUNDATION |
发明人 |
ABBOTT NICHOLAS L.;CLARE BRIAN H. |
分类号 |
G01N31/00 |
主分类号 |
G01N31/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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