发明名称 |
COMBINATION THERAPY FOR THE TREATMENT OF DIABETES AND CONDITIONS RELATED THERETO AND FOR THE TREATMENT OF CONDITIONS AMELIORATED BY INCREASING A BLOOD GLP-1 LEVEL |
摘要 |
The present invention concerns combination of an amount of a GPRl 19 agonist with an amount of a dipeptidyl peptidase IV (DPP-IV) inhibitor such that the combination provides an effect in lowering a blood glucose level or in increasing a blood GLP-I level in a subject over that provided by the amount of the GPRl 19 agonist or the amount of the DPP-FV inhibitor alone and the use of such a combination for treating or preventing diabetes and conditions related thereto or conditions ameliorated by increasing a blood GLP-I level. The present invention also relates to the use of a G protein-coupled receptor to screen for GLP-I secretagogues.
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申请公布号 |
KR20100072085(A) |
申请公布日期 |
2010.06.29 |
申请号 |
KR20107010978 |
申请日期 |
2006.01.09 |
申请人 |
ARENA PHARMACEUTICALS, INC. |
发明人 |
CHU ZHI LIANG;LEONARD JAMES N.;AL SHAMMA HUSSIEN A.;JONES ROBERT M. |
分类号 |
A61K31/505;A61K31/401;A61K31/513;A61P3/10 |
主分类号 |
A61K31/505 |
代理机构 |
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地址 |
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