发明名称 Crystalline N-(4-(4-aminothieno[2,3-d]pyrimidin-5-yl)phenyl)-N′-(2-fluoro-5-(trifluoromethyl)phenyl)urea ethanolate
摘要 A crystalline N-(4-(4-aminothieno[2,3 -d]pyrimidin-5-yl)phenyl)-N′-(2-fluoro-5-(trifluoromethyl)phenyl)urea ethanolate characterized in the monoclinic crystal system and P21/n space group, when measured with radiation at 0.7107 Å, by lattice parameters a, b and c of 5.0318 ű0.006 Å, 23.684 ű0.002 Å and 18.877 ű0.002 Å, respectively, and &bgr; of 90.703±0.003, ways to make it, compositions comprising it, and methods of treatment using it are disclosed.
申请公布号 US7745448(B2) 申请公布日期 2010.06.29
申请号 US20060642395 申请日期 2006.12.20
申请人 ABBOTT LABORATORIES INC. 发明人 MELLICAN SEAN M.;LINTON CATHIE L.;MEI JIANZHANG;TEDROW JASON S.;CHARUKAMNOETKANOK NAHATHAI;HENRY RODGER
分类号 C07D495/04;A61K31/519;A61P9/12;A61P17/06;A61P35/02;A61P35/04 主分类号 C07D495/04
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