发明名称 METHOD FOR ASSESSMENT OF VASCULAR WALL ADAPTATION TO FUNCTIONAL LOAD
摘要 FIELD: medicine. ^ SUBSTANCE: before and after local ischemia, diametre of the brachial artery, blood nitrite level, endothelin concentration and Willebrand factor are evaluated. The accommodation of vascular wall endotheliocytes to ischemia is calculated by formula that describes a coefficient Ken. If Ken is "0" or less, the adaptation of the vascular wall is considered as preserved; Ken within "0" to 0.2 inclusive shows the moderately lowered adaptation of the vascular wall, while the Ken value exceeding 0.2 indicates the considerably lowered adaptation of the vascular wall. The coefficient Ken may be used for a quantitative estimation of specific features of cell functional adaptation to ischemic factors, both in norm, and in cardiovascular pathology. ^ EFFECT: use of the invention allows reducing the acquisition time in 3 times, objectively assessing the endothelium adaptation to ischemia. ^ 3 ex
申请公布号 RU2393477(C1) 申请公布日期 2010.06.27
申请号 RU20080150311 申请日期 2008.12.18
申请人 GOSUDARSTVENNOE UCHREZHDENIE NAUCHNYJ TSENTR REKONSTRUKTIVNOJ I VOSSTANOVITEL'NOJ KHIRURGII VOSTOCHNO-SIBIRSKOGO NAUCHNOGO-TSENTRA SIBIRSKOGO OTDELENIJA ROSSIJSKOJ AKADEMII MEDITSINSKIKH NAUK 发明人 PIVOVAROV JURIJ IVANOVICH;KORJAKINA LARISA BORISOVNA;ANDREEVA ELENA ORESTOVNA;KURIL'SKAJA TAT'JANA EFIMOVNA;CHIZHOVA ELENA ANATOL'EVNA;TJURJUMINA ELENA EHDUARDOVNA
分类号 G01N33/52;G01N33/53 主分类号 G01N33/52
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