| 摘要 |
FIELD: medicine, pharmaceutics. ^ SUBSTANCE: present invention refers to an oral pharmaceutical composition taken between meals for phosphorous compounds absorption from the intestinal liquids, especially from saliva. The composition contains a phosphorus binding agent, and a pharmaceutically acceptable carrier and/or an excipient. The composition is kept in a mouth to exhaust the phosphorus binding agent. The phosphorus binding agent represents a phosphate binding agent polymer, a pharmaceutically acceptable lanthanum salt, a pharmaceutically acceptable magnesium salt, a pharmaceutically acceptable calcium salt, a pharmaceutically acceptable anion-exchange resin, a pharmaceutically acceptable phosphate binding polysaccharide. Preferentially, the agent represents phosphate binding chitosan. The composition is used for treating hyperphosphatemia. ^ EFFECT: invention provides effective treatment of high blood serum phosphorus concentration and reduces risk of cardiovascular complications in patients. ^ 19 cl, 2 tbl, 2 ex |
