发明名称 Benzoxazole-2-one derivatives as lipase and phospholipase inhibitors
摘要 Disclosed is a benzoxazole-2-one derivative as represented by formula I, wherein R1 is alkyl or alkylene-aryl, where aryl may be substituted one or more times by halogen, alkyl, alkyloxy, hydroxy, amino, alkylamino or trifluoromelhyl; R2 is hydrogen, and the other substituents are as defined herein. Also disclosed is the use of a compound as defined above for producing a medicament for the treatment and/or prevention of disorders of fatty acid metabolism and glucose utilization disorders, disorders in which insulin resistance Is involved, diabetes mellitus, dyslipidemias, conditions associated with the metabolic syndrome, conditions associated with reduced HDL level and atherosclerotic disorders.
申请公布号 NZ564062(A) 申请公布日期 2010.06.25
申请号 NZ20060564062 申请日期 2006.05.27
申请人 SANOFI-AVENTIS 发明人 ZOLLER, GERHARD;PETRY, STEFAN;HEUER, HUBERT;TENNAGELS, NORBERT;MULLER, GUNTER
分类号 C07D263/58;A61K31/421;A61K31/423 主分类号 C07D263/58
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