发明名称 |
METHODS RELATED TO MODIFIED GLYCANS |
摘要 |
<p>Among other things, the present disclosure provides methods for enriching, identifying, and/or quantifying unusually modified glycans (e.g., phosphorylated glycans, sulfated glycans, and/or multi-acetylated glycans). In many embodiments, methods comprise providing a glycan preparation from which sialic acids have been released; subjecting the sialidase-treated glycan preparation to a separation technique that separates glycans based on charge-to-mass ratio; and quantifying the charged products using at least one quantification standard.</p> |
申请公布号 |
CA2743181(A1) |
申请公布日期 |
2010.06.24 |
申请号 |
CA20092743181 |
申请日期 |
2009.12.18 |
申请人 |
MOMENTA PHARMACEUTICALS, INC. |
发明人 |
BOSQUES, CARLOS J.;MURPHY, JENNIFER LYNN;GUNAY, SIBEL NUR;SHRIVER, ZACHARY;LIU, CUIHUA |
分类号 |
C07H15/14;A61K38/14;C07H5/10 |
主分类号 |
C07H15/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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