| 发明名称 |
HEPATITIS-C-VIRUS-IMPFSTOFF |
| 摘要 |
The present invention provides recombinant nucleic acids comprising one or more Ad6 regions and a region not present in Ad6, where the Ad6 region is selected from E1A, E1B, E2B, E2A, E4, L1, L2, L4 and L5, preferably where the adenovirus is defective in E1 but is able to replicate when E1 is supplied in trans. |
| 申请公布号 |
DE60236364(D1) |
申请公布日期 |
2010.06.24 |
| 申请号 |
DE2002636364 |
申请日期 |
2002.10.10 |
| 申请人 |
ISTITUTO DI RICHERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A.;MERCK SHARP & DOHME CORP. |
发明人 |
EMINI, EMILIO A.;KASLOW, DAVID C.;BETT, ANDREW J.;SHIVER, JOHN W.;NICOSIA, ALFREDO;LAHM, ARMIN;LUZZAGO, ALESSANDRA;CORTESE, RICCARDO;COLLOCA, STEFANO |
| 分类号 |
C12N15/09;C12N15/40;A61K35/76;A61K38/00;A61K39/00;A61K48/00;A61P31/14;C07K14/18;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N15/51;C12N15/85;C12N15/86;C12N15/861 |
主分类号 |
C12N15/09 |
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