| 发明名称 |
SOLUBLE POLYPEPTIDES FOR USE IN TREATING AUTOIMMUNE AND INFLAMMATORY DISORDERS |
| 摘要 |
<p>The present invention relates to soluble CD47 binding polypeptides, for use as a medicament, in particular for the prevention or treatment of autoimmune and inflammatory disorders, for example allergic asthma and inflammatory bowel diseases. The Invention more specifically relates to a soluble CD47 binding polypeptide for use as a medicament, comprising an extracellular domain of SIRPa (CD172a) or functional derivatives which bind to human CD47.</p> |
| 申请公布号 |
WO2010070047(A1) |
申请公布日期 |
2010.06.24 |
| 申请号 |
WO2009EP67411 |
申请日期 |
2009.12.17 |
| 申请人 |
NOVARTIS AG;RAYMOND, MARIANNE;SARFATI, MARIE;WELZENBACH, KARL;WOISETSCHLAEGER, MAXIMILIAN |
发明人 |
RAYMOND, MARIANNE;SARFATI, MARIE;WELZENBACH, KARL;WOISETSCHLAEGER, MAXIMILIAN |
| 分类号 |
C07K14/435;A61K38/17;C07K14/705;C12N1/15;C12N1/21;C12N5/10;C12N15/68 |
主分类号 |
C07K14/435 |
| 代理机构 |
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