发明名称 MALEATE SALTS OF (E)-N-{4-[3-CHLORO-4-(2-PYRIDINYLMETHOXY)ANILINO]-3-CYANO-7-ETHOXY-6-QUINOLINYL}-4-(DIMETHYLAMINO)-2-BUTENAMIDE AND CRYSTALLINE FORMS THEREOF
摘要 The present invention relates to maleate salt forms of (E)-N-{4-[3-chloro-4-(2-pyridinylmethoxy)anilino]-3-cyano-7-ethoxy-6-quinolinyl}-4-(dimethylamino)-2-butenamide, methods of preparing crystalline maleate salt forms, the associated compounds, and pharmaceutical compositions containing the same. The maleate salts are useful in treating cancers, particularly those affected by kinases of the epidermal growth factor receptor family.
申请公布号 KR20100069708(A) 申请公布日期 2010.06.24
申请号 KR20107010637 申请日期 2008.10.16
申请人 WYETH LLC 发明人 LU QINGHONG;KU MANNCHING SHERRY;CHEW WARRREN;CHEAL GLORIA K.;HADFIELD ANTHONY F.;MIRMEHRABI MAHMOUD
分类号 C07D401/14;A61K31/404;A61P35/00;C07D401/12 主分类号 C07D401/14
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