发明名称 |
Extended-Release Pharmaceutical Formulations |
摘要 |
The present invention provides matrix-forming, sustained-release pharmaceutical formulations comprising four primary components: i) an effective amount of at least one drug substance; ii) at least one pharmaceutically acceptable, water-swellable, pH independent polymer; iii) at least one pharmaceutically-acceptable, anionic, pH dependent polymer; and (iv) a pharmaceutically-acceptable polymer selected from the group consisting of a) at least one pharmaceutically-acceptable cationic polymer; and b) at least one pharmaceutically acceptable hydrocolloid. The present formulations can be used with compounds having a wide range of solubilities as well as compounds characterized as having hydrophobic or hydrophilic characteristics.
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申请公布号 |
US2010159001(A1) |
申请公布日期 |
2010.06.24 |
申请号 |
US20080339529 |
申请日期 |
2008.12.19 |
申请人 |
CARDINAL JOHN R;JAMES JACK LAWRENCE;MELSOPP ELSIE;OAKLEY DAVID M |
发明人 |
CARDINAL JOHN R.;JAMES JACK LAWRENCE;MELSOPP ELSIE;OAKLEY DAVID M. |
分类号 |
A61K9/52;A61K9/00;A61K9/28 |
主分类号 |
A61K9/52 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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