| 发明名称 |
QUINAZOLINES USEFUL AS MODULATORS OF ION CHANNELS |
| 摘要 |
The present invention relates to compounds useful as inhibitors of voltage-gated sodium channels and calcium channels. The invention also provides pharmaceutically acceptable compositions comprising the compounds of the invention and methods of using the compositions in the treatment of various disorders.
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| 申请公布号 |
US2010160316(A1) |
申请公布日期 |
2010.06.24 |
| 申请号 |
US20100714871 |
申请日期 |
2010.03.01 |
| 申请人 |
VERTEX PHARMACEUTICALS INCORPORATED |
发明人 |
GONZALEZ, III JESUS E.;WILSON DEAN M.;TERMIN ANDREAS P.;GROOTENHUIS PETER D. J.;ZHANG YULIAN;PETZOLDT BENJAMIN J.;FANNING LEV TYLER DEWEY;NEUBERT TIMOTHY D.;TUNG ROGER D.;MARTINBOROUGH ESTHER;ZIMMERMAN NICOLE |
| 分类号 |
A61K31/5377;A61K31/496;A61K31/517;A61K31/541;A61P11/00;A61P13/02;A61P17/02;A61P19/02;A61P19/10;A61P21/00;C07D239/86;C07D239/88;C07D403/04;C07D413/02;C07D413/10;C07D417/02 |
主分类号 |
A61K31/5377 |
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