摘要 |
The present invention describes Stable injectable oil-in-water Docetaxel nanoemulsion composition having Docetaxel concentrations as high as 20 mg/ml, devoid of hypersensitivity reaction and fluid retention,. It employs Synthetic triglycerides, and DSPE PEG-2000, Natural phosphatides, Polyhydric alcohol and Water for injection. In another embodiment lyophilised products with added Cryoprotectants have been described which on reconstitution gives nanoemulsion suitable for parenteral administration. |
申请人 |
BHARAT SERUMS AND VACCINES LTD.;DAFTARY, GAUTAM, VINOD;PAI, SRIKANTH, ANNAPPA;KULKARNI, MANGESH, MANIKRAO |
发明人 |
DAFTARY, GAUTAM, VINOD;PAI, SRIKANTH, ANNAPPA;KULKARNI, MANGESH, MANIKRAO |