发明名称 |
Screening of Abundantly Secreted Proteins and Their Use as Fusion Partners for the Production of Recombinant Proteins |
摘要 |
The present invention relates techniques for identifying suitable secretion fusion partner (SFP) for hyper-secretory production of recombinant proteins. The SFPs can be obtained from secretome analyses. Recombinant proteins are produced in a fusion form with a secretion fusion partner (SFP) and can be separated from the SFP by in vitro protease treatment. SFPs of this invention greatly improve the secretion level of target proteins and peptides which are valuable for bio-pharmaceuticals and the bio-industry.
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申请公布号 |
US2010159465(A1) |
申请公布日期 |
2010.06.24 |
申请号 |
US20090631449 |
申请日期 |
2009.12.04 |
申请人 |
KOREAN RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
发明人 |
SOHN JUNG-HOON;BAE JUNG-HOON;KIM HYUN-JIN;LIM KWANG-MOOK;KIM SEUNG LI |
分类号 |
C12Q1/68;C07K14/00;C07K14/54;C07K14/575;C07K14/745;C07K14/755;C07K14/765;C12N1/15;C12N1/19;C12N1/21;C12N5/10;C12N9/96;C12N15/63;C12P21/00 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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