| 摘要 |
The present invention is directed to 1,2,5-oxadiazole derivatives, and compositions of the same, which are inhibitors of indoleamine 2,3-dioxygenase and are useful in the treatment of cancer and other disorders, and to the processes and intermediates for making such 1,2,5-oxadiazole derivatives. The present invention provides, inter alia, IDO inhibitors of Formula I: or a pharmaceutically acceptable salt thereof, wherein: R1 is NH2 or CH3; R2 is C1, Br, CF3, CH3, or CN; R3 is H or F; and n is 1 or 2. |
| 申请人 |
INCYTE CORPORATION;COMBS, ANDREW, P.;YUE, EDDY, W.;SPARKS, RICHARD, B.;ZHU, WENYU;ZHOU, JIACHENG;LIN, QIYAN;WENG, LINGKAI;YUE, TAI-YUEN;LIU, PINGLI |
发明人 |
COMBS, ANDREW, P.;YUE, EDDY, W.;SPARKS, RICHARD, B.;ZHU, WENYU;ZHOU, JIACHENG;LIN, QIYAN;WENG, LINGKAI;YUE, TAI-YUEN;LIU, PINGLI |
