| 发明名称 |
Lawsonia intracellularis cultivation, anti-Lawsonia intracellularis vaccines and diagnostic agents |
| 摘要 |
<p>A method for large scale cultivation and attenuation of L . intracellularis bacteria by inoculating cells with L. intracellularis bacteria to infect the cells, incubating the infected cells in a reduced oxygen concentration and maintaining the infected cells in suspension. Anti- L . intracellularis vaccines are prepared from cultures grown in suspension. Diagnostic agents are also disclosed.</p> |
| 申请公布号 |
EP2199795(A2) |
申请公布日期 |
2010.06.23 |
| 申请号 |
EP20100150886 |
申请日期 |
1996.06.05 |
| 申请人 |
BOEHRINGER INGELHEIM VETMEDICA, INC. |
发明人 |
ROOF, MICHAEL B.;KNITTEL, JEFFREY P. |
| 分类号 |
G01N33/554;A61K39/02;A61K39/106;A61K39/40;A61P31/04;C07K16/12;C12N1/00;C12N1/20;C12N1/36;C12N5/06;C12N9/92;C12Q1/02;G01N33/569 |
主分类号 |
G01N33/554 |
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