CELL EXPRESSING DOPAMINE D1 RECEPTOR AND METHOD OF DEVELOPING NOVEL DRUGS USING THE CELL

摘要

PURPOSE: A polynucleotide which is able to over-express dopamine D1 receptor and a transformant thereof are provided to develop a novel drug from natural product or herb material. CONSTITUTION: A polynucleotide which is able to express dopamine D1 receptor comprises a nucleotide of sequence number 2. An expression vector of mammal cells comprises a polynucleotide having a nucleotide of sequence number 2. A transformant is obtained by transducing the polynucleotide of sequence number 2 to a host cell. The host cell is BHK(baby hamster kidney) cell, CHO(Chinese hamster ovary) cell, mouse embryonic fibroblast cell line, human embryonic kidney, or myeloma cell.