发明名称 |
GLUCOPYRANOSYLOXYPYRAZOLE DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF, AND INTERMEDIATE THEREFOR |
摘要 |
A glucopyranosyloxypyrazole derivative represented by the following general formula (I), a pharmaceutically acceptable salt of the derivative, or a prodrug of either. (I) The compound has excellent inhibitory activity against human SGLT1 and is useful as a preventive or remedy for diseases attributable to hyperglycemia such as diabetes, complications of diabetes, and obesity. Also provided are a medicinal composition containing the derivative, salt, or prodrug; a medicinal use thereof; and an intermediate for the derivative. (In the general formula (I), R1 is hydrogen, etc.; one of Q and T is the group represented by (II) and the other is optionally substituted alkyl, etc.; and R2 is halogeno, etc.)
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申请公布号 |
CA2448741(C) |
申请公布日期 |
2010.06.22 |
申请号 |
CA20022448741 |
申请日期 |
2002.05.27 |
申请人 |
KISSEI PHARMACEUTICAL CO., LTD. |
发明人 |
SHIOHARA, HIROAKI;FUJIKURA, HIDEKI;FUSHIMI, NOBUHIKO;ITO, FUMIAKI;ISAJI, MASAYUKI |
分类号 |
C07H17/02;A61K31/7056;A61P3/04;A61P3/10;A61P43/00;C07D231/20;C07H15/26 |
主分类号 |
C07H17/02 |
代理机构 |
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