发明名称 |
Enhanced oral and transcompartmental delivery of therapeutic or diagnostic agents |
摘要 |
The invention is directed to pharmaceutical compositions and methods for delivery of a therapeutic or diagnostic agent from one bodily compartment to one or more other bodily compartment by administering one of the following conjugates: a polymer having multiple functional groups at least one of which is covalently bound to a therapeutic or diagnostic agent, and at least one cell uptake promoter covalently bound to the therapeutic or diagnostic agent; or a polymer and at least one cell uptake promoter bound thereto; the polymer further comprising multiple functional groups at least one of which is covalently bound a therapeutic or diagnostic agent. |
申请公布号 |
US7740882(B2) |
申请公布日期 |
2010.06.22 |
申请号 |
US20050170652 |
申请日期 |
2005.06.29 |
申请人 |
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发明人 |
RAMANATHAN SRINIVASAN;STEIN STANLEY;LEIBOWITZ MICHAEL;SINKO PATRICK J.;MINKO TAMARA;WILLIAMS GREGORY C.;ZHANG GOUBAO;ZHANG XIAOPING;POOYAN SHAHRAIR;PARK SEONG HEE;QIU BO;PARANJPE PANKAJ |
分类号 |
A61K9/20;A61K38/00;A61K38/04;A61K47/48;A61K51/00 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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