| 摘要 |
The present invention refers to a process for the obtention of high performance probiotic biomass from lactic acid bacteria, for instance of the Lactobacillis genus, particularly Lactobacillus casei, resulting from whey by a process including: (a) optionally skimming and ultra filtering the raw material for recovering protein (which optionally may be obtained by irrigation or preferably by lyophilisation for the obtention of a second product of high value), (b) a fed-batch or continuous fermentation, (c) and preferably recovering and lyophilising the resulting probiotic biomass. The present invention includes significant advantages over batch processes previously reported for the obtention of probiotoc bacteria from supplemented whey. Some advantages are the following: (a) significantly improving the yield (g biomass/g substrate); (b) improving the process productivity (g biomass/L-hr); (c) reducing the death times of the process ; (d) improving the quality of the product, expressed a s viable cells/gr of biomass; (e) potential obtention of valuable byproducts (protein, fat and lactic acid).
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