| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide solutions including multiple active agents to inhibit inflammation, inhibit pain, effect mydriasis (dilation of the pupil), and/or decrease the intraocular pressure in operation, wherein the solutions are prepared for intraocular topological delivery of the multiple agents to act on multiple differing molecular targets. <P>SOLUTION: The solutions are irrigating solutions during an ophthalmologic procedure which is used to inhibit inflammation, inhibit pain, effect mydriasis, and/or decrease intraocular pressure, wherein the solution includes at least a first and a second agent in a liquid irrigation carrier. The first and second agents are selected to act on a plurality of differing molecular targets, and each agent (IOP reducing agent) is selected from the physiologic functional classes of anti-inflammatory agents, analgesic agents, mydriatic agents and agents for decreasing intraocular pressure. The second agent provides at least one physiologic function different from a function or functions provided by the first agent, and each agent is contained at a concentration of 100,000 nM or less. <P>COPYRIGHT: (C)2010,JPO&INPIT |
