Isolated human monoclonal antibodies which bind to human TF and related antibody- based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the antibodies, and therapeutic and diagnostic methods for using the antibodies.
申请公布号
CA2746101(A1)
申请公布日期
2010.06.17
申请号
CA20092746101
申请日期
2009.12.09
申请人
GENMAB A/S
发明人
VERPLOEGEN, SANDRA;SATIJN, DAVID P. E.;HOET, RENE M. A.;PARREN, PAUL;VAN DE WINKEL, JAN;BREINHOLT, VIBEKE MILLER;EHRNROOTH, EVA;BAADSGAARD, OLE;VINK, TOM;BLEEKER, WILLEM KAREL;HOUTKAMP, MISCHA;OUDSHOORN, MAROESKA;DE JONG, ROB N.