发明名称 ANTIBODIES WITH ALTERED BINDING TO FCRN AND METHODS OF USING SAME
摘要 This invention relates to antibodies with altered binding to FcRn, and particularly antibodies having enhanced binding to FcRn and/or enhanced serum half-lives. The invention also relates to methods of using the antibodies and compositions comprising them in the diagnosis, prognosis and therapy of diseases such as cancer, autoimmune diseases, inflammatory disorders, and infectious disease.
申请公布号 WO2010033279(A3) 申请公布日期 2010.06.17
申请号 WO2009US46214 申请日期 2009.06.04
申请人 MACROGENICS, INC.;GORLATOV, SERGEY 发明人 GORLATOV, SERGEY
分类号 A61K39/00 主分类号 A61K39/00
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