PROLIFERATION-ASSOCIATED MODULATION OF THE SPLICING OF THE INTEGRIN ALPHA 6 ISOFORMS

摘要

This application relates to the use of agents such as expression vectors and nucleic acids encoding integrins a6A or a6B which are capable of modulating the ratio between the B and A isoforms of the a6 integrin the treatment of diseases associated with an altered proliferation rate, such as cancer This application also relates to the use of the ratio between the B and A isoforms of the a6 integrin in the diagnosis of diseases associated with an altered proliferation rate.