A PREPARATION METHOD OF VENLAFAXINE SUSTAINED RELEASE FORMULATION

摘要

A preparation method of venlafaxine sustained-release formulation is disclosed. It comprises the steps of dispersing venlafaxine and binder into isopropanol to form a suspension, spraying the suspension onto the sugar spheres to form the drug pellets, making aqueous suspension of talc and well mixing it with a polyacrylic resin water-dispersion, and then, spraying the talc-polyacrylic resin suspension onto the drug pellets to form said micropellet formulation with a slow-release coating.